Utilizing the folate receptor for active targeting of cancer nanotherapeutics
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چکیده
منابع مشابه
Utilizing the folate receptor for active targeting of cancer nanotherapeutics
The development of specialized nanoparticles for use in the detection and treatment of cancer is increasing. Methods are being proposed and tested that could target treatments more directly to cancer cells, which could lead to higher efficacy and reduced toxicity, possibly even eliminating the adverse effects of damage to the immune system and the loss of quick replicating cells. In this mini-r...
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Promising targeted treatments and immunotherapy strategies in oncology and advancements in our understanding of molecular pathways that underpin cancer development have reignited interest in the tumor-associated antigen Folate Receptor alpha (FRα). FRα is a glycosylphosphatidylinositol (GPI)-anchored membrane protein. Its overexpression in tumors such as ovarian, breast and lung cancers, low an...
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ژورنال
عنوان ژورنال: Nano Reviews
سال: 2012
ISSN: 2000-5121
DOI: 10.3402/nano.v3i0.18496